Lyell

South San Francisco, CA Biotechnology Public

Lyell is a clinical-stage cell therapy company dedicated to advancing next-generation CAR T-cell product candidates for patients with hematologic malignancies and solid tumors. The company pioneers novel approaches designed to generate T cells with potent cancer cell killing capabilities that drive long-lasting clinical responses, leveraging proprietary ex vivo genetic (Gen-R) and epigenetic (Epi-R) reprogramming technology platforms.

Public Company

Lyell is publicly traded

IPO'd on June 17, 2021

LYEL NASDAQ

This company is no longer available on our private secondary market. Shares can be traded publicly under LYEL.

Overview

Company data and valuation marks are estimates and may be incomplete, stale, erroneous, or revised.

Founded

2018

Employees

220–300

Total Funding

$834M

3 rounds

Funding

Total raised $834M across 3 rounds

Funding data and valuation marks are estimates and may be incomplete, stale, erroneous, or revised.

Last updated 06-25-2026

Latest Round

Type

Series C

Date

March 2020

Amount

$493M

Valuation

Lead Investors

Not disclosed
DateRoundAmount RaisedValuationLead Investors
March 2020 Series C $493M Not disclosed
2019 Series A $179M ARCH Venture Partners
2019 Series B $162M Not disclosed

Leadership

  • Lynn Seely, M.D.

    President and Chief Executive Officer

  • Rick Klausner, M.D.

    Founder & Chairman of the Board

  • Crystal Mackall, M.D.

    Founder

  • Stan Riddell, M.D.

    Founder

  • Gary Lee, Ph.D.

    Chief Scientific Officer

  • Stephen Hill, M.B.A.

    Chief Operating Officer

  • David Shook, M.D.

    Chief Medical Officer

  • Smital Shah

    Chief Financial and Business Officer

Competitors

Competitor list is illustrative and may be incomplete, stale, or erroneous.

  • Juno Therapeutics

    Developer of CAR-T cell therapies for hematologic malignancies; acquired by Bristol-Myers Squibb.

  • Kite Pharma

    Commercial leader in CAR-T therapies for lymphoma and leukemia; acquired by Gilead Sciences.

  • Orca Bio

    Cell therapy company developing allogeneic CAR-T treatments; partnership with Lyell for solid tumors.

  • Achilles Therapeutics

    Cell therapy company developing personalized T-cell therapies for cancer.

Lyell Investment FAQ

Lyell FAQ

Yes, Lyell is publicly traded under the ticker symbol LYEL on the NASDAQ. The company went public in June 17, 2021.

Lyell trades under the ticker symbol LYEL on the NASDAQ. It began trading in June 17, 2021.

Lyell (LYEL on the NASDAQ) shares can be purchased through any standard brokerage account — including Fidelity, Charles Schwab, TD Ameritrade, and online platforms like Robinhood or E*TRADE. Search for the ticker LYEL to place an order.

Lyell went public in June 17, 2021 via ipo. Lyell Immunopharma went public on NASDAQ under ticker LYEL on June 17, 2021, raising $425 million in its IPO at $17.00 per share. The company is the third largest biotech IPO in history.

Lyell raised $834M across 3 disclosed funding rounds prior to its public listing.

Lyell was co-founded by Rick Klausner, M.D., Crystal Mackall, M.D., and Stan Riddell, M.D. in 2018.

Lyell is headquartered in South San Francisco, CA.

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