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Orbital Therapeutics

Cambridge, Massachusetts, United States Healthcare Acquired

Orbital Therapeutics is an RNA medicines biotechnology company building a platform that combines RNA technology, delivery methods, data science and automation to develop medicines in next-generation vaccines, immunomodulation and protein replacement. Its lead program, OTX-201, is an investigational in vivo CAR T-cell therapy targeting autoimmune disease through B cell depletion. Founded in 2022 as a spin-out from Beam Therapeutics, Orbital was acquired by Bristol Myers Squibb in December 2025 for $1.7 billion ($1.5 billion net of cash acquired).

Acquired

Orbital Therapeutics has been acquired

Acquired by Bristol Myers Squibb Dec 8, 2025 $1.7B ($1.5B net of cash acquired)

This company is no longer available on our private secondary market.

Overview

Company data and valuation marks are estimates and may be incomplete, stale, erroneous, or revised.

Founded

2022

Employees

11–50

Total Funding

$270M

1 rounds

Secondary Signals (Note: SetterVC does not verify the accuracy of these)

1 signal
M&A Recent $1.7B total consideration; $1.5B net of cash acquired 2025-12-08

Bristol Myers Squibb completed its all-cash acquisition of Orbital Therapeutics for $1.7B ($1.5B net of cash acquired)

Company now BMS-owned; no private-market secondary liquidity remains

Funding

Funding data and valuation marks are estimates and may be incomplete, stale, erroneous, or revised.

Total raised $270M across 1 rounds

Last updated 10-09-2026

DateRoundAmount RaisedValuationLead Investors
Apr 26, 2023 Series A Press release $270M — ARCH Venture Partners

Prominent Investors

New Form Capital GSRV Psalion Luminous Futures Golden Record Ventures

Leadership

  • Ron Philip

    Chief Executive Officer

  • Giuseppe Ciaramella

    Co-Founder

  • Jonathan Piazza

    Chief Financial Officer

  • Niru Subramanian

    Chief Operating Officer

  • Gilles Besin

    Chief Scientific Officer

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