
Valo Health is a technology-driven drug discovery and development company that integrates human-centric data, artificial intelligence, advanced causal inference, and predictive chemistry into a unified platform called the Opal Computational Platform. Founded and incubated by Flagship Pioneering in 2019, Valo aims to compress drug development timelines and improve probability of success by combining real-world clinical data, human genetics, 3D engineered human tissue models, and closed-loop chemistry to discover and advance small-molecule therapies. The company has built a pipeline focused on cardiometabolic, oncology, and neurodegenerative diseases, and has formed major partnerships including an expanded January 2025 collaboration with Novo Nordisk worth up to approximately $4.6 billion in milestones plus $190 million in near-term payments, equity, and R&D funding. Headquartered in Lexington, Massachusetts, with additional offices in New York and historically in Tel Aviv, Valo terminated a $750 million SPAC merger with Khosla Ventures Acquisition Co. in November 2021 and has remained private since.
Company data and valuation marks are estimates and may be incomplete, stale, erroneous, or revised.
Founded
2019
Employees
201–500
Total Funding
$568.5M
5 rounds
Total raised $568.5M across 5 rounds
Funding data and valuation marks are estimates and may be incomplete, stale, erroneous, or revised.
Last updated 06-25-2026
Latest Round
Type
PIPE (SPAC withdrawn)
Date
June 9, 2021
Amount
$168.5M
Valuation
$2.8B
Lead Investors
| Date | Round | Amount Raised | Valuation | Lead Investors |
|---|---|---|---|---|
| January 2025 | Strategic equity (Novo Nordisk) | Not disclosed | — | Novo Nordisk |
| June 9, 2021 | PIPE (SPAC withdrawn) | $168.5M | $2.8B | Khosla Ventures |
| March 9, 2021 | Series B (final close) | $110M | — | Koch Disruptive Technologies |
Brian M. Alexander
Chief Executive Officer
Christian Schade
Executive Chairman
Graeme Bell
Executive Vice President & Chief Financial Officer
David Berry
Founder
Competitor list is illustrative and may be incomplete, stale, or erroneous.
Recursion Pharmaceuticals
Public AI-driven drug discovery company operating an end-to-end Operating System combining high-throughput biology, phenomics, and machine learning to identify drug candidates.
Insilico Medicine
End-to-end AI drug discovery company using generative AI across target discovery, molecule design, and clinical outcome prediction, with advanced pipeline programs in fibrosis and oncology.
Schrodinger
Computational chemistry leader combining physics-based molecular modeling and machine learning to power both internal pipeline programs and a software-licensing business serving pharma.
Isomorphic Labs
Alphabet-owned AI drug discovery company spun out of DeepMind, applying AlphaFold-derived structural prediction and generative AI to small-molecule discovery in partnership with Novartis and Eli Lilly.
Exscientia
AI-driven precision drug design company (acquired by Recursion in 2024) focused on automated molecule design, patient-tissue-driven target identification, and pharma partnerships.
Owkin
AI biotech using federated learning across hospital networks to extract clinical and multi-omic insights for drug target discovery and biomarker development.
No. Valo Health is a private company and does not have a public stock ticker or trade on a public stock exchange. Its shares are generally held by founders, employees, investors, and other private shareholders. Buyers and sellers may be able to transact in Valo Health shares through private secondary transactions, but any transaction depends on share availability, buyer and seller agreement, transfer restrictions, company approval rights, and any applicable right of first refusal. There is no guarantee that Valo Health will complete an IPO or other liquidity event.
Yes, it is sometimes possible to buy Valo Health shares pre-IPO through private secondary transactions. This depends on finding a willing seller, company approval, and satisfying any transfer restrictions or rights of first refusal.
Buyers interested in buying Valo Health shares on the secondary market typically do so through SetterVC and other secondary-market platforms, subject to eligibility requirements, share availability, transfer restrictions, and issuer approval. Buyers may need to satisfy sophistication, accreditation, institutional, platform, regulatory, or other eligibility requirements before participating. Once eligible, buyers may be able to view listings, make bids, and work with a licensed broker through the transaction process. Buyers should ensure they have appropriate legal and financial advisors guiding them before completing any transaction.
SetterVC currently shows one valuation mark for Valo Health based on funding rounds, tender offers, secondary-market indications, and other reported or collected valuation marks. Valo Health's valuation was approximately $2.8B as of June 9, 2021. Secondary-market prices may differ from this valuation based on share class, transaction size, transfer restrictions, supply and demand, company performance, and broader market conditions. SetterVC and Setter Capital does not verify the accuracy or completeness of valuation data, and buyers and sellers should confirm current information before relying on it.
Valo Health's latest disclosed funding round was a Strategic equity (Novo Nordisk) round in January 2025. The round raised approximately Not disclosed, with Novo Nordisk listed as disclosed lead or major investors. Primary funding rounds are different from secondary transactions: in a primary round, capital goes to the company, while in a secondary transaction, investors buy existing shares from current shareholders. Funding-round data reflects publicly reported or collected information and may be incomplete.
Valo Health has raised approximately $568.5M in disclosed funding across 5 rounds. These figures reflect primary capital raised by the company and do not include every possible secondary transaction, undisclosed round, debt facility, or private transfer. Reported funding totals can change as new rounds are announced or older round details are corrected. Eligible users can use SetterVC to track Valo Health's funding history alongside private-market activity where available.
Valo Health's disclosed investors include Novo Nordisk, Khosla Ventures, Koch Disruptive Technologies and Flagship Pioneering. Investor lists are based on public reporting, company announcements, and collected funding-round data, and may be incomplete. Participation in a prior funding round does not mean those investors are currently buying or selling shares. On SetterVC, eligible users can review Valo Health's funding history, valuation history, and private-market activity alongside other venture-backed companies.
Valo Health's most-cited competitors include Recursion Pharmaceuticals, Insilico Medicine, Schrodinger, Isomorphic Labs, Exscientia and Owkin. Investors often compare these companies by sector, product focus, valuation, funding raised, growth signals, investor base, and private-market activity.
Secondary-market demand for Valo Health shares can be affected by company performance, revenue growth, profitability, funding history, valuation, investor interest, sector momentum, public-market conditions, expected timing of a liquidity event, and the availability of shares for sale. Demand can also be affected by transfer restrictions, company approval rights, right of first refusal processes, limited information, and the price expectations of buyers and sellers. Strong demand does not guarantee strong pricing, liquidity, or investment returns. Weak demand does not necessarily reflect the company's long-term prospects. Demand signals should not be treated as a recommendation or prediction of investment performance. Buyers and sellers should treat demand signals as informational and conduct their own diligence before transacting.
Sellers often rely on intermediaries and platforms, such as SetterVC and other secondary-market platforms, to identify potential buyers. The exact process varies by company and transaction, but sellers often begin by confirming their ownership, desired price, transferability, and any company approval or notice requirements. If the seller agrees with a buyer on acceptable price and terms, the company may need to be notified through a share transfer notice or similar process. If a right of first refusal, company approval right, or other transfer restriction applies, the seller may need to wait until that process is completed. The parties may then execute a purchase and sale agreement, complete required transfer documentation, and close if all required conditions are satisfied. Sellers should always seek proper legal and financial advice before completing the transaction.
Yes, current and former Valo Health employees, early investors, and other existing shareholders may be able to sell vested shares before an IPO through a private secondary sale. This is not automatic; it depends on whether the shareholder has transferable shares, whether there is buyer demand, and whether the company's governing documents permit the transfer. Many companies require prior notice, company approval, or a right of first refusal before shares can be sold. Sellers should also seek proper legal and financial advice before proceeding.
A Valo Health secondary transaction usually involves an existing shareholder selling shares to a buyer before a public listing. The buyer and seller typically agree on price, number of shares, share class, and closing conditions. The seller may then need to notify Valo Health through a share transfer notice or similar process. If Valo Health or existing investors have approval rights, transfer restrictions, or a right of first refusal, those steps may need to be completed before the transfer can close. The parties typically enter into a purchase and sale agreement, complete any required transfer documentation, and close only if the necessary conditions are satisfied. Timing and certainty can vary by company and transaction.
In most private secondary transactions, parties commonly use a purchase and sale agreement that outlines price, terms, and conditions. They may also use share transfer documentation, often a stock transfer notice, share transfer notice, transfer instruction, or similar document, along with any required company approval or right of first refusal materials. Proof of ownership, such as a cap table entry, share certificate, brokerage statement, issuer confirmation, or administrator confirmation, may also be important. Buyers often request recent company financials, but private companies may limit disclosure. Since every deal varies, buyers and sellers should consult legal and financial advisors to understand which documents are needed.
Buying Valo Health shares pre-IPO is risky. Shares are illiquid, no IPO or liquidity event is guaranteed, valuations can change, transfers may require company approval, and private companies may provide limited financial disclosure. Be prepared for total loss. SetterVC and Setter Capital do not provide due diligence, legal, tax, accounting, valuation, or investment advice. Buyers must conduct their own due diligence, verify information, and seek independent legal and investment advice before proceeding.
Private secondary shares are typically illiquid. Unlike public stocks, there is no active public market, so selling them can be difficult and time-consuming. Sales depend on finding a willing buyer and often require company approval. Investors should be prepared to hold the shares for an extended period, with no guarantee of a future sale. Always assess your need for liquidity before investing.
SetterVC and Setter Capital do not provide due diligence, legal, tax, accounting, valuation, or investment advice. Buyers must conduct their own due diligence, including verifying ownership, transferability, legal structure, company approval, and assessing the company's prospects. SetterVC and Setter Capital do not provide advice on whether an investment is good, what price to pay, or what the best bid or ask is. SetterVC and Setter Capital may share documents in some circumstances, but it does not guarantee their accuracy or completeness. Due diligence is essential. Seek legal and investment advice as needed.
Before buying Valo Health shares, a buyer should try to review the share class, price per share, implied valuation, transfer restrictions, ROFR process, company approval rights, seller ownership evidence, recent financing or tender-offer information, available financial information, information rights, resale restrictions, tax considerations, and expected liquidity paths. Not all information may be available for a private company. Buyers should confirm available diligence, process details, and information needs with their own legal, tax, and investment advisers.
SPVs carry risks. Examples include the need to confirm the company allows SPV-based transfers, verify that the SPV truly owns the shares or interests it claims to own, and ensure it has not sold more interests than it holds. Due diligence is essential. Seek legal and investment advice as needed.
Forward contracts carry risks. Examples include the seller refusing to transfer the shares at the future date, even if the seller owns them, the seller going bankrupt with creditors claiming the shares, or the seller committing the same shares to multiple parties. Due diligence is essential. Seek legal and investment advice as needed.
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